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  • Title: Erythromycin and clindamycin resistance in Corynebacterium diphtheriae from skin lesions.
    Author: Coyle MB, Minshew BH, Bland JA, Hsu PC.
    Journal: Antimicrob Agents Chemother; 1979 Oct; 16(4):525-7. PubMed ID: 117748.
    Abstract:
    Erythromycin- and clindamycin-resistant Corynebacterium diphtheriae isolates were recovered from skin lesions. Resistance to erythromycin and clindamycin was induced by a subinhibitory concentration (0.03 microgram/ml) of erythromycin. Clindamycin (0.07 microgram/ml) was a more effective inducer of its own resistance than of erythromycin resistance. Erythromycin-inducible cross-resistance to vernamycin B alpha was demonstrated in disk diffusion tests.
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