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  • Title: Allogeneic stem cell transplantation for Evans syndrome.
    Author: Oyama Y, Papadopoulos EB, Miranda M, Traynor AE, Burt RK.
    Journal: Bone Marrow Transplant; 2001 Nov; 28(9):903-5. PubMed ID: 11781654.
    Abstract:
    Evans syndrome is a rare disorder characterized by combined autoimmune thrombocytopenia (ITP) and autoimmune hemolytic anemia (AIHA). Standard treatments consist of transfusions, corticosteroids, splenectomy, IVIG, anabolic steroids, vincristine, alkylating agents, or cyclosporine. In a patient with refractory disease, an allogeneic hematopoietic stem cell transplant (HSCT) resulted in complete clinical and serologic remission for more than 30 months. Allogeneic HSCT may be the only current curative therapy for Evans syndrome but may also be complicated by significant toxicities.
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