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  • Title: [Study on effect of delivery way on thyrotropin levels in pregnant women and their newborns].
    Author: Wang Y, Liu R, Guo J.
    Journal: Zhonghua Fu Chan Ke Za Zhi; 2001 May; 36(5):282-4. PubMed ID: 11783377.
    Abstract:
    OBJECTIVE: To investigate the effect on thyrotropin (TSH) levels of pregnant women and their newborns in different delivery ways. METHODS: The serum TSH levels of 213 pregnant women and the umbilical cord blood TSH levels of their newborns (140 cases from normal vaginal delivery, 38 cases from cesarean section, 35 cases from low forceps delivery) were tested by immunoradiometric assay. Urinary iodine was detected from pregnant women before delivery. RESULTS: In pregnant women, the mean serum level of TSH in the forceps group [(4.13 +/- 0.69) mU/L] was significantly higher than those of the normal birth group [(2.58 +/- 0.87) mU/L, P < 0.01] and the cesarean section group [(2.81 +/- 0.45) mU/L, P < 0.01]. There was no difference in TSH level between the normal birth group and the cesarean section group. In newborns, the mean TSH level in the forceps group [(8.85 +/- 2.48) mU/L] was significantly higher than those of the normal birth group [(5.36 +/- 2.23) mU/L, P < 0.01] and the cesarean section group [(3.84 +/- 2.16) mU/L, P < 0.01]. The mean TSH level in the normal birth group was significantly higher than that of the cesarean section group (P < 0.05). The serum TSH levels of pregnant women were positively correlated with the umbilical cord blood TSH levels of their newborns in three groups. CONCLUSIONS: The contraction of uterus is the stimulus for the surge in TSH levels of pregnant women and their newborns after delivery. It's reliable that the TSH levels of newborns could be evaluated by monitoring the TSH levels of pregnant woman.
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