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  • Title: [Technetium polyphosphate and technetium diphosphonate. A comparative study].
    Author: Henne W, Pixberg HU, Pfannenstiel P.
    Journal: Nucl Med (Stuttg); 1975 Jun 30; 14(2):83-90. PubMed ID: 1178518.
    Abstract:
    99mTc-labelled phosphates are the bone seeking agents of choice. The comparison of 99mTc-polyphosphate (Poly-P) and 99mTc-ethane-1-hydroxy-1,1-diphosphonate (EHDP) shows a better in vitro stability of the latter during the first two hours after preparation. The blood clearance of EHDP is superior to Poly-P resulting in reduced background activity at scanning time. Renal excretion over a 4-hour period of urine sampling showed no significant differences between both substances. Blood activity is independent of diuresis.
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