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  • Title: Thyroid metabolism in the recessive sex-linked dwarf female chicken. 4. The influence of exogenous thyroid hormones on amino acid uptake by plasma and tissues.
    Author: Grandhi RR, Brown RG, Reinhart BS, Summers JD.
    Journal: Poult Sci; 1975 Mar; 54(2):503-9. PubMed ID: 1178608.
    Abstract:
    The influence of exogenous triiodothyronine (T3) or tetraiodothyronine (T4) on the incorporation of 3H-labelled methionine, alanine and lysine into plasma, liver and kidney was studied in 4 wk. old dwarf and non-dwarf female, White Leghorn chickens. The response to exogenous T3 or T4 of the birds was directly dependent on the dwarf status as well as the tissue and/or amino acid studied. In general, there was a decreased amino acid uptake by dwarfs and T3 and/or T4 depressed amino acid uptake in all combinations studied except for the uptake of lysine by the kidney of the dwarf. In that tissue, T4 administration caused a significant increase in lysine incorporation. The results found probably were due to different tissue amino compositions or rates of synthesis of proteins by dwarf birds when compared to normals and a differential sensitivity of dwarf birds to changed T3/T4 ratios.
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