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  • Title: Optimal treatment of nevirapine-associated hepatotoxicity remains uncertain.
    Author: Bundow D, Rosoff L, Aboulafia DM.
    Journal: AIDS Read; 2001 Nov; 11(11):577-80. PubMed ID: 11789021.
    Abstract:
    The cases of 2 patients with nevirapine-associated hepatotoxicity in conjunction with rash and eosinophilia are reported here. Both patients' conditions improved following withdrawal of nevirapine. Previous case reports have described a variety of interventions other than drug withdrawal that might have contributed to resolution of drug-induced hepatitis. Until a better understanding of the clinical spectrum and pathophysiology of nevirapine-associated hepatotoxicity is realized, treatment will remain largely empiric.
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