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  • Title: First-stage palliation of complex univentricular cardiac anomalies in older infants.
    Author: Duncan BW, Rosenthal GL, Jones TK, Lupinetti FM.
    Journal: Ann Thorac Surg; 2001 Dec; 72(6):2077-80. PubMed ID: 11789797.
    Abstract:
    BACKGROUND: Poor outcomes have been reported for children older than 30 days of age with cardiac anomalies treated with first-stage palliation. METHODS: Our institution has offered first-stage palliation for all such patients regardless of age. The results of this policy were reviewed. RESULTS: Nine patients older than 30 days (median age 67 days, range 36 to 108 days) with diagnoses of hypoplastic left heart syndrome (n = 5), double-outlet right ventricle with hypoplastic aortic arch (n = 2), unbalanced atrioventricular septal defect (n = 1), or single left ventricle with subaortic stenosis (n = 1) underwent surgical palliation. Patients underwent a Norwood (n = 7) or Damus-Kaye-Stancel (n = 2) procedure with a 4- or 5-mm modified Blalock-Taussig shunt; all patients survived the operation. Eight patients underwent a subsequent bidirectional Glenn (2 perioperative deaths, both due to pneumonia; 6 survivors). Two of the 6 surviving patients have undergone Fontan reconstruction and 4 are awaiting Fontan. CONCLUSIONS: Surgical palliation for complex univentricular cardiac malformations can be performed in older infants with results comparable to those in neonates. The use of a larger shunt may contribute to these improved outcomes.
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