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  • Title: Histopathological changes in gills of the estuarine crab Chasmagnathus granulata (Crustacea-Decapoda) following acute exposure to ammonia.
    Author: de Freitas Rebelo M, Rodriguez EM, Santos EA, Ansaldo M.
    Journal: Comp Biochem Physiol C Toxicol Pharmacol; 2000 Feb; 125(2):157-64. PubMed ID: 11790338.
    Abstract:
    Histopathological effects of ammonia on the gills of the estuarine crab Chasmagnathus granulata (Dana, 1851) were evaluated after acute exposure to ammonia concentrations around LC(50) value (17.85 Mm). Disruption of pilaster cells and a subsequent collapse of gill lamellae were the main effects observed. Epithelial necrosis and hyperplasia were also detected. Significant (P<0.05) increases in pCO(2) and lactate, and significant decreases of pO(2) were detected in the haemolymph of ammonia-exposed crabs. These changes suggest that the observed histopathological damage affected gas exchange, possibly leading to death.
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