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  • Title: [Fucosidosis and blood group substances in the urine].
    Author: Tchilian MJ, Lemonnier M, Font J, Bourrillon R, Cartron J, Bamberger J.
    Journal: C R Seances Acad Sci D; 1979 Jul 09; 289(2):193-6. PubMed ID: 117924.
    Abstract:
    Glycopeptide and oligosaccharide fractions obtained from fucosidosis urine contains more Lea activity (4-8 fold) than control urine. Both fucosidosis fractions also contained Leb and H activities, no A activity in contrast to the salivary and erythrocyte phenotypes (A, Le a+ b-). The amount of Leb activity is lower in both fractions (1) and (2) than that of Leb control children (4-16 fold decrease). Blood group A activity was not detected at any concentration used (less than or equal to 50 fold-concentrated urine) whereas A activity was found in (A, Le a- b+) control urine. On the contrary, both fucosidosis fractions contained H activity, whereas A (Le a- b+) control children fractions had none (less than or equal to 50-fold concentrated urine). H and Leb activity might originate from Lea precursor apart from the "non-secretory" type of the patient.
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