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  • Title: Directionality and processivity of molecular motors.
    Author: Higuchi H, Endow SA.
    Journal: Curr Opin Cell Biol; 2002 Feb; 14(1):50-7. PubMed ID: 11792544.
    Abstract:
    Analysis of a mutant with altered directionality has led to new insights into motor directionality. The prediction from current models for processivity of a two-heads-bound state has been confirmed by electron microscopy for myosin V and by unbinding experiments for kinesin. Evidence is emerging that non-processive motors bind their filament with one head, hydrolyze ATP and then release, requiring binding by a second motor to complete a step.
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