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Title: Principles of cargo attachment to cytoplasmic motor proteins. Author: Kamal A, Goldstein LS. Journal: Curr Opin Cell Biol; 2002 Feb; 14(1):63-8. PubMed ID: 11792546. Abstract: The attachment of cytoskeletal motor proteins to cargo-laden vesicles is crucial for efficient transport in intracellular membrane trafficking pathways. Recent studies have identified specific kinesin-binding and dynein-binding proteins that could serve as membrane-associated 'receptor' proteins for the respective motors. New insights have also emerged about the cargo-binding domains of the motor proteins, and the regulation of motor binding to cargoes.[Abstract] [Full Text] [Related] [New Search]