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  • Title: Fatal hypernatraemia after hypertonic saline irrigation of hepatic hydatid cysts.
    Author: Krige JE, Millar AJ, Rode H, Knobel D.
    Journal: Pediatr Surg Int; 2002 Jan; 18(1):64-5. PubMed ID: 11793068.
    Abstract:
    A 7-year-old boy with hepatic hydatid cysts developed fatal hypernatraemia after surgery for cyst removal where 20% hypertonic saline (HS) was used as a scolicidal agent. Symptoms of generalised seizures, tachycardia, and hypotension developed within 6 h of surgery. Serum electrolytes confirmed hypernatraemia (170 mmol/l) and hyperchloraemia (141 mmol/l). Despite attempts at resuscitation, he died 20 h later. The literature is reviewed, emphasising the potential dangers of the use of HS and the clinical presentation and appropriate management of hypernatraemia.
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