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Title: [Low-osmolar gadodiamide as alternative contrast agent for diagnostic angiography and angiographic interventions in patients with renal insufficiency]. Author: Dinkel HP, Hoppe H, Baumgartner I, Do DD, Triller J. Journal: Rofo; 2002 Jan; 174(1):56-61. PubMed ID: 11793285. Abstract: PURPOSE: To evaluate the benefit and feasibility of gadolinium contrast agents for intra-arterial use in diagnostic and therapeutic angiography in patients with renal insufficiency. METHODS: In 15 patients with planned peripheral or renal vascular interventions digital subtraction angiography with intra-arterial administration of gadolinium (gadodiamide n = 14, gadolinium-DTPA n = 1) was performed. Gadolinium was used selectively after peripheral catheter placement, mainly as an adjunct to CO2 (n = 12), to assess the distal run-off vessels or to characterize stenotic lesions. RESULTS: In 14 cases gadolinium yielded good or satisfactory results that were superior to those of CO2 angiography in the femoropopliteal region and calf, but also to the aorto-iliac vessels and the renal arteries. A small amount of iodinated contrast media was administered due to insufficient contrast of gadolinium in one patient. Mean serum creatinine level after angiography (295 +/- 167 micromol/l; range 125 - 764 micromol/l) was not significantly different (p >/= 0,37) from the initial level (279 +/- 149 micromol/l; range 143 - 728 micromol/l). CONCLUSION: Gadolinium is a viable alternative contrast agent for digital subtraction angiography and percutaneous transluminal angioplasty in patients with renal insufficiency. It enhances the diagnostic evaluation of stenosis and run-off vessels.[Abstract] [Full Text] [Related] [New Search]