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  • Title: MEN-2A syndrome and pulmonary metastasis.
    Author: Alfaro JJ, Lamas C, Estrada J, Lucas T.
    Journal: Postgrad Med J; 2002 Jan; 78(915):51-2. PubMed ID: 11796876.
    Abstract:
    A case of multiple endocrine neoplasia syndrome type-2A (MEN-2A) with primary hyperparathyroidism and medullary carcinoma of thyroid initially treated by surgery is reported. The presence of pulmonary nodules six years after the initial treatment was thought to be related to metastasis of medullary carcinoma, and the increase in serum calcium concentrations was assumed to be caused by persistence of parathyroid adenomatous or hyperplastic tissue. The patient underwent surgery again and the pulmonary nodules were confirmed to be metastases of a parathyroid carcinoma, a very rare entity in MEN-2A syndrome.
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