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  • Title: Second German consensus on immunogenetic donor search for allotransplantation of hematopoietic stem cells.
    Author: Ottinger HD, Müller CR, Goldmann SF, Albert E, Arnold R, Beelen DW, Blasczyk R, Bunjes D, Casper J, Ebell W, Ehninger G, Eiermann T, Einsele H, Fauser A, Ferencik S, Finke J, Hertenstein B, Heyll A, Klingebiel T, Knipper A, Kremens B, Kolb HJ, Kolbe K, Lenartz E, Lindemann M, Müller CA, Mytilineos J, Niederwieser D, Runde V, Sayer H, Schaefer UW, Schmitz N, Schröder S, Schulze-Rath R, Schwerdtfeger R, Siegert W, Thiele B, Zander AR, Grosse-Wilde H.
    Journal: Ann Hematol; 2001 Dec; 80(12):706-14. PubMed ID: 11797110.
    Abstract:
    The present paper summarizes the results of the second German consensus meeting on immunogenetic donor search for allotransplantation of hematopoietic stem cells held in Essen in November 1999 under the auspices of the German Society for Immunogenetics (DGI) and the German Working Party for Blood and Marrow Transplantation (DAG-KBT). Immunogeneticists and transplant physicians from all over the country agreed to update the national standards for: (1) search strategy including the role of unrelated and extended family donor search after unsuccessful core family donor search, (2) histocompatibility loci to be typed, (3) histocompatibility typing techniques to be used (HLA serology vs DNA-based HLA typing, cellular tests, serum cross-match), and (4) acceptable HLA mismatches in the context of a defined underlying disease, donor type, and conditioning regimen.
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