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  • Title: [Alkaline phosphatase].
    Author: Fukatsu T.
    Journal: Rinsho Byori; 2001 Nov; Suppl 116():27-35. PubMed ID: 11797377.
    Abstract:
    High levels of alkaline phosphatase activity are characteristic of bone disease with increased osteoblastic activity, hepatobiliary disease with partial or complete biliary obstruction and transient hyperphosphatasemia in children. A gamma-glutamyl transpeptidase is often useful to differentiate whether an elevated alkaline phosphatase originates in the bones or the liver. A normal gamma-glutamyl transpeptidase suggests bone origin. A serum alkaline phosphatase isozyme pattern by electrophoresis is also necessary to differentiate various pathological states.
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