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  • Title: Use of morphine and adjuvant drugs according to the condition.
    Author: Matoba M.
    Journal: Eur J Pain; 2001; 5 Suppl A():59-62. PubMed ID: 11798219.
    Abstract:
    Adjuvant drugs are used to enhance effects of analgesics and morphine-resistant pain such as neuropathic pain. If morphine provides inadequate pain relief and evokes drowsiness, morphine is usually ineffective. The key is the patient's reaction to morphine. When a patient's pain includes neuropathic pain, a combination of morphine and non-steroidal anti-inflammatory drugs is partially effective, but morphine-resistant pain remains. Increasing morphine dosage causes drowsiness without pain improvement. Appropriate adjuvant drugs are necessary in these conditions.
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