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  • Title: [The effects of the polysaccharides from Dermatocarpon miniatum on oxygen radicals and lipid peroxidation].
    Author: Jin J, Bian X, Ge P, Jing H, Ding L, Ding D.
    Journal: Zhong Yao Cai; 2001 Sep; 24(9):660-1. PubMed ID: 11799779.
    Abstract:
    OBJECTIVE: To study the effects of Dermatocarpon miniatum (DEM) polysaccharides scavenging oxygen radicals and inhibiting lipid peroxidation. METHODS: .OH was produced by Fenton reaction and O2-. was produced by the oxidation of pyrogallol. The inhibition to LPO was determined by the colorimetry for testing the relative content of MDA. RESULTS: DEM polysaccharides could scavenge oxygen radical. The amounts of scavenging 50% (EC50) .OH was 1.72 mg/ml, the EC50 for O2-. was 2.12 mg/ml. DEM polysaccharides could also decrease the content of MDA. CONCLUSION: DEM polysaccharides has the effects of scavenging oxygen radicals and the inhibition to LPO. Its activities showed positive correlation with the amounts.
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