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Title: Nucleic acid probes in periodontal diagnosis. Author: Mahesh CP, Nayak D. Journal: Indian J Dent Res; 2001; 12(3):181-3. PubMed ID: 11808070. Abstract: Periodontal Disease is considered as an infection caused by a variety of microorganisms. Considering the vast range of microbial species involved in the causation of periodontal diseases, a specific diagnostic procedure, to identify the various organisms involved is a major necessity. A number of diagnostic procedures, including microbiological and immunological have been utilized in the diagnosis of periodontal disease. The DNA probe technology provides both a sensitive and specific assay and also alleviates concern for transport of the fastidious microorganisms in clinical samples, fulfills the need for a specific and rapid test, that does not require the preservation of viable microorganisms. DNA probes are now being used to identify the various putative pathogen's including; A. actinomycetemcomitans, P. gingivalis, P. intermedia, B. forsythus, etc. Besides DNA probes have also been proven an advantage over the various other available procedures in periodontal diagnosis.[Abstract] [Full Text] [Related] [New Search]