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  • Title: Alcohol-water as a novel medium for beta-hematin preparation.
    Author: Blauer G, Akkawi M.
    Journal: Arch Biochem Biophys; 2002 Feb 01; 398(1):7-11. PubMed ID: 11811943.
    Abstract:
    It is shown that alcohol-water mixtures (e.g., 43 wt% ethanol) provide a suitable medium for the efficient production in high yield of beta-hematin from ferriprotoporphyrin IX (FP), as measured by infrared spectroscopy. Previous and present light-absorption data of FP, obtained under specific acid conditions in an ethanol-water medium, suggest the presence of FP monomers, which are considered to promote the reaction leading to beta-hematin. Other aspects of the mechanism of reaction are discussed.
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