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  • Title: Thalidomide therapy for recalcitrant systemic onset juvenile rheumatoid arthritis.
    Author: Lehman TJ, Striegel KH, Onel KB.
    Journal: J Pediatr; 2002 Jan; 140(1):125-7. PubMed ID: 11815776.
    Abstract:
    Systemic onset juvenile rheumatoid arthritis unresponsive to nonsteroidal anti-inflammatory drugs may be controlled with corticosteroids, but these drugs have significant side effects. We report 2 steroid-dependent children with systemic onset juvenile rheumatoid arthritis who did not respond to multiple nonsteroidal anti-inflammatory drugs, methotrexate, azathioprine, cyclosporine, and etanercept. Both children had significant improvement with thalidomide therapy.
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