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  • Title: Two-carrier models for mediated transport. II. Glucose and galactose equilibrium exchange experiments in human erythrocytes as a test for several two-carrier models.
    Author: Eilam Y.
    Journal: Biochim Biophys Acta; 1975 Sep 02; 401(3):364-9. PubMed ID: 1182144.
    Abstract:
    1. Equilibrium exchange of glucose and of galactose is measured in human erythrocytes over wide concentration ranges. One-site Michaelis-Menten-type kinetics are shown for the two sugars. 2. In view of the results, two of the two-carrier models discussed in paper I (Eilam, Y. (1975) Biochim. Biophys. Acta 401, 349-363), the different sequential carriers and the antiparallel simultaneous carriers, are rejected for the sugar transfer system. The antiparallel sequential carriers model is consistent with these results.
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