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  • Title: [Language and learning disorders in epilepsy with continuous spike-waves during slow sleep].
    Author: Billard-Daudu C.
    Journal: Epileptic Disord; 2001; 3 Spec No 2():SI77-85. PubMed ID: 11827850.
    Abstract:
    Efficacy of antiepileptic drugs in children with epilepsy is usually evaluated on the basis of reduction in seizure frequency. However, in a number of cases, the effect of a drug in reducing EEG paroxysmal activity should be considered. This applies particularly to Landau-Kleffner syndrome and to the syndrome of continuous spike-waves during slow sleep. In developmental language disorders, EEG paroxysmal activity is present in almost 30% of the cases. Paroxysmal abnormalities are usually less frequent than what is observed in epilepsy with continuous spike-waves during slow sleep. Pathogenesis remains unknown and the relationship between EEG evolution and language improvement is not as clear as in Landau-Kleffner syndrome.
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