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  • Title: [The study of ultrastructure of retinal pigment epithelium of transplantation].
    Author: Li G, Wu L, Gao R, Wu D.
    Journal: Zhonghua Yan Ke Za Zhi; 1999 Jan; 35(1):50-1, 2. PubMed ID: 11835776.
    Abstract:
    OBJECTIVE: To investigate the ultrastructure of retinal pigment epithelium (RPE) for the base of clinical application. METHODS: Pigmented rabbit RPE was transplanted to the subretinal space of 10 unpigmented rabbits by internal route. The ultrastructure of transplanted RPE cells were observed by electron microscopy. RESULTS: The transplantation of RPE was successful. It was shown that the transplanted cells had polarity and attached to Bruch's membrane to form basal infoldings, and the relationships between transplanted cells and the host photoreceptors were also seen. CONCLUSIONS: The internal approach is a practical and useful method for transplantation of RPE. The transplanted RPE can vitalize, perform metabolism and form some normal ultrastructure.
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