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  • Title: [Study of the mechanism of action of the new antidepressant pyrazidol].
    Author: Mashkovskiĭ MD, Gorkin VZ, Andreeva NI, Verevkina IV, Siniukhin VN.
    Journal: Farmakol Toksikol; 1975; 38(5):531-6. PubMed ID: 1183581.
    Abstract:
    The biochemical mechanism of action produced by a new antidepressant pyrazidol (1,10-trimethylene-8-methyl-1, 2, 3, 4-tetrahydropyrazino[1,2-a] indole hydrochloride) includes the inhibitory influence on the neuronal uptake of norepinephrine and a reversible comparatively short-lived inhibitory effect on the MAO activity.
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