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  • Title: Metabolites from fungi 15. New isocoumarins from an endophytic fungus isolated from the Canadian thistle Cirsium arvense.
    Author: Krohn K, Flörke U, Rao MS, Steingröver K, Aust HJ, Draeger S, Schulz B.
    Journal: Nat Prod Lett; 2001; 15(5):353-61. PubMed ID: 11841120.
    Abstract:
    One known (1) and five new polyketide metabolites (2-6) were isolated from the culture extract of an endophytic fungus, Mycelia sterila, from the Canadian thistle Cirsium arvense. Compounds 1-4 are members of the isocoumarin family, whereas metabolite 5 is a dihydrobenzofuran and 6 has an open chain structure. All compounds have an unusual methyl group at the aromatic ring that does not fit into the usual polyketide pattern.
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