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  • Title: [Study on the compliance of antihypertensive drugs in patients with hypertension].
    Author: Guo H, He H, Jiang J.
    Journal: Zhonghua Liu Xing Bing Xue Za Zhi; 2001 Dec; 22(6):418-20. PubMed ID: 11851054.
    Abstract:
    OBJECTIVE: To study the compliance of antihypertensive drugs and its related factors in inpatients and outpatients patients with hypertension. METHOD: Clinical data of 816 inpatients and 497 outpatients were reviewed to study the compliance of antihypertensive drugs and related factors as well as to investigate the utilization of anti-hypertensive medicament, the incidence of the side-effect of the medication and to explore the difference of the blood pressure control between the compliant group and the uncompliant group. RESULTS: The main risk factors of the hypertensive patients were in the order as: disorder of lipometabolism, smoking, left ventricular hypertrophy (LVH) and Diabetes mellitus. Sixty point nine percent of the inpatients were followed up. The incidences of compliance were 63.4% in the inpatients, 77.3% when being discharged, and 43.7% in the outpatients. The cause of uncompliance were as follows: side-effect of the medication, failure to control BP, financial problems, etc. Data gathered during follow up period, it was found the side effect of the calcium antagonist and the diuretics improved palpably. Those compliers controlled their BP well, while little fluctuation of BP was observed. However, the uncompliers showed different pictures, and the range of fluctuation of BP was large. CONCLUSIONS: The compliance of the medicament was best among the outpatients to the discharge order, and the compliance of the outpatients was the worst.
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