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  • Title: [A preliminary report of ocular surface disease treated by limbal transplantation].
    Author: Xie L, Dong X, Shi W, Cui Y, Li S.
    Journal: Zhonghua Yan Ke Za Zhi; 2000 Nov; 36(6):449-51, 30. PubMed ID: 11853647.
    Abstract:
    OBJECTIVE: To evaluate the effect of ocular surface disease treated by limbal transplantation. METHODS: In a prospective study, 5l eyes of 50 patients were treated with three kinds of surgical techniques: first, conjunctival limbal autograft (CLAU) transplantation; second, corneal lamellar allograft combined with limbal autograft transplantation and third, corneal lamellar allograft combined with limbal allograft transplantation. Their effects were evaluated. RESULTS: All of the 18 patients of CLAU group were cured. The second surgical technique resulted in restoration of a stable ocular surface in 19 of 20 cases. 10 patients' visual acuities were improved two or more than two lines. 13 eyes of 12 patients were treated with the third surgical technique, resulting in graft ulceration in 4 patients and graft rejection in 4 patients with bad prognosis. CONCLUSIONS: The effect of unilateral ocular surface disease treated with limbal autograft transplantation is satisfactory. For bilateral ocular surface disease, the method of limbal allograft transplantation should be improved to resolve some problems such as graft rejection.
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