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  • Title: Subcarinal bronchogenic cyst with high carbohydrate antigen 19-9 production.
    Author: Okabayashi K, Motohiro A, Ueda H, Ondo K, Kawahara K, Shirakusa T.
    Journal: Jpn J Thorac Cardiovasc Surg; 2002 Jan; 50(1):46-8. PubMed ID: 11855101.
    Abstract:
    In a rare case of bronchogenic cyst with high carbohydrate antigen (CA) 19-9 production, a 57-year-old man with coughing and chest pain was diagnosed with a subcarinal mediastinal tumor. Fiberoptic bronchoscopy showed an erosive mucosal lesion overlying the area of extrinsic compression at the membranous of the right mainstem bronchus. Serum carbohydrate antigen 19-9 was elevated at 1300 U/ml. Thoracotomy showed an encapsulated cyst tightly adhering to the right main bronchus. The cyst was extirpated after ablation at the adherent cystic wall by electrocautery. Although intracystic carbohydrate antigen 19-9 concentration was very high, serum carbohydrate antigen 19-9 and bronchoscopic findings returned to normal postoperatively. The histological diagnosis was consistent with a bronchogenic cyst and carbohydrate antigen 19-9 could be immunohistochemically demonstrated within its epithelium.
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