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  • Title: [The effectiveness of cyclosporin A in the treatment of autoimmune hemolytic anemia and Evans syndrome].
    Author: Liu H, Shao Z, Jing L.
    Journal: Zhonghua Xue Ye Xue Za Zhi; 2001 Nov; 22(11):581-3. PubMed ID: 11855146.
    Abstract:
    OBJECTIVE: To test the therapeutic effectiveness of cyclosporin A (CsA) in combination with corticosteroid in the treatment of autoimmune hemolytic anemia(AIHA) and Evans syndrome. METHODS: Forty-four cases of AIHA and Evans syndrome were treated with CsA in combination with a conventional regimen (prednisone + danazol) (18 cases) or conventional regimen alone(26 cases). RESULTS: The complete response rate of CsA group (88.9%) was higher than that of conventional regimen group (57.7%) (P < 0.05), and the relapse rate was lower (3.3% vs 70%) (P < 0.01). CONCLUSION: CsA in combination with conventional regimen can improve the complete response rate and reduce relapse of AIHA and Evans syndrome.
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