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  • Title: Treatment of steroid-resistant idiopathic thrombocytopenic purpura in pregnancy with repeated high-dose intravenous immunoglobulin.
    Author: Kimura S, Kuroda J, Akaogi T, Hayashi H, Ogino Y, Kobayashi Y, Yoshikawa T.
    Journal: Haematologia (Budap); 2001; 31(3):263-5. PubMed ID: 11855790.
    Abstract:
    High-dose intravenous immunoglobulin (HD-IVIG) has temporary but reliable efficacy in idiopathic thrombocytopenic purpura (ITP). HD-IVIG has been described as the representative management in pregnant cases of refractory to corticosteroid or immunosuppressants. There have been few cases treated with repeated HD-IVIG to sustain pregnancy from the early phase of pregnancy. This case report describes a pregnant case of steroid-refractory ITP, treated with six times repeated HD-IVIG, resulting in the successful delivery of a healthy newborn with a normal platelet count. No adverse effects were observed.
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