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  • Title: Dental disease indices and caries related oral microflora in children with phenylketonuria.
    Author: Lucas VS, Contreras A, Loukissa M, Roberts GJ.
    Journal: ASDC J Dent Child; 2001; 68(4):263-7, 229. PubMed ID: 11862879.
    Abstract:
    The purpose of this study was to investigate the dental caries, plaque and gingivitis indices and caries related oral flora in children with classic phenylketonuria. Forty-one children at The Great Ormond Street Hospital for Children and controls were included in the study. The main findings were: No significant difference in the decayed, missing and filled surfaces of the primary and permanent teeth between the phenylketonuria children and the controls. A significantly greater mean plaque score for the control children compared with the phenylketonuria children (p < 0.01) for the permanent teeth only. A significantly greater number of white opacities in the permanent teeth of the phenylketonuria group compared with the control group (p < 0.02). No significant differences in the caries related microflora.
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