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  • Title: Varicella-zoster virus acquired at 4 months of age reactivates at 24 months and causes encephalitis.
    Author: Chiappini E, Calabri G, Galli L, Salvi G, de Martino M.
    Journal: J Pediatr; 2002 Feb; 140(2):250-1. PubMed ID: 11865281.
    Abstract:
    Varicella-zoster virus (VZV) reactivation in the brain caused encephalitis in a 2-year-old immunocompetent child who had chickenpox 20 months before. Radiologic findings were consistent with large to medium-vessel-vasculitis. VZV-DNA was detected in cerebrospinal fluid. Early acquisition of VZV may predispose to major neurologic complications that can occur years after the primary infection.
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