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PUBMED FOR HANDHELDS

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  • Title: [Is heart rate reduction beneficial to patients with heart insufficiency? Focus on beta-blockade].
    Author: Henriksen OM, Gadsbøll N.
    Journal: Ugeskr Laeger; 2002 Jan 28; 164(5):615-9. PubMed ID: 11871210.
    Abstract:
    The aim of this review was to assess the effect of pharmacological reduction of the heart rate on prognosis in patients with chronic heart failure. Although a high heart rate is associated with a reduced life expectancy and causes a number of unwanted pathophysiological effects on the failing heart, there is no documentation that the beneficial effect of beta-blockers or other heart failure agents on survival is mediated through a reduction in heart rate.
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