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  • Title: Exercise-induced asthma in children with intrinsic and extrinsic asthma.
    Author: Eggleston PA.
    Journal: Pediatrics; 1975 Nov; 56(5 pt-2 suppl):856-9. PubMed ID: 1187275.
    Abstract:
    The significance of intrinsic asthma as a diagnosis has been questioned since, except for the lack of evidence of allergy, there is no pathophysiologic distinction from extrinsic asthma. Following a standardized exercise stress, allergic (extrinsic) asthmatics respond with more severe asthma than do nonallergic (intrinsic) asthmatics. The incidence of significant exercise-induced asthma is greater in a group of extrinsic asthmatics than in intrinsic asthmatics. Extrinsic asthmatics show increased airway sensitivity during a significant pollen season.
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