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  • Title: [Histopathological evaluation of orbital tissue encircling intraorbital implant made of glassy carbon and its influence on basic blood parameters in a rabbit].
    Author: Kokot W, Iwaszkiewicz-Bilikiewicz B, Rozpłoch F, de Laval W.
    Journal: Klin Oczna; 2001; 103(2-3):85-90. PubMed ID: 11873417.
    Abstract:
    PURPOSE: The purpose of the study is to present histopathological evaluation of orbital tissue encircling intraorbital implant and to present influence of glassy carbon on blood parameters of rabbits. MATERIAL AND METHODS: We examined 20 rabbits (Oryctolagus Cuniculus) and 2 pigs (Suis Domesticus) with carbon orbital implants. Periodically the experimental animals were killed 5, 20, 35, 60, 100, 150 days after implantation of glassy carbon into the orbit. Encircling tissue was histopathologically examined. The blood was taken to analysis on 0, 5, 20, 35, 60, 100, 150 day after procedure. RESULTS: Histopathological specimens of rabbits did not show intolerance reaction of glassy carbon. Histopathological picture was typical of the "foreign body" reaction. Histopathological pictures of pigs did not show any reaction to implant. There was no deviation in blood parameters. CONCLUSIONS: We suggest that intraorbital glassy carbon implants do not induct intolerance reactions to orbital tissues. Glassy carbon implant does not have any influence on basic blood parameters of rabbits.
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