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  • Title: A facile method for the preparation of N6-substituted ATP-Sepharose.
    Author: Eckstein F, Goumet M, Wetzel R.
    Journal: Nucleic Acids Res; 1975 Oct; 2(10):1771-5. PubMed ID: 1187346.
    Abstract:
    The attachment of 6-methylsulfonylpurineribose 5'-triphosphate to AH-Sepharose 4B as a facile method for the preparation of ATP-Sepharose is described. This reaction is compared to the coupling of 6-chloropurineriboside 5'-triphosphate as well as N(6)-aminocaproyl-ATP. An improved synthesis of purineriboside 5'-phosphates which does not require purification by column chromatography is also described.
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