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  • Title: [Three cases with a mediastinal neurinoma developed in a same family].
    Author: Harada H, Matsuoka H, Nishio W, Sakamoto T, Yuki T, Tsubota N.
    Journal: Kyobu Geka; 2002 Mar; 55(3):267-9. PubMed ID: 11889820.
    Abstract:
    A 47-years-old woman (case 1) was admitted to our hospital because of a mediastinal mass. We performed an operation by VATS under the diagnosis of a mediastinal neurinoma. The histology of it was a neurinoma. Her father (case 2) had undergone a resection of a mediastinal neurinoma at the age of 42. Her brother (case 3) also had undergone a resection of mediastinal and intrathoracic neurinomas at the age of 37. A few years later, he underwent operations for neurinomas in limbs 2 times. We suppose patients with a mediastinal neurinoma have little complaints in many cases, so there are a number of patients who have a mediastinal neurinoma without being discovered and treated. Although the neurinoma is not considered as a hereditary disease inherently, the cases, we experienced, might have some genetic disorders. In this concern, our cases are very rare and have a great interest.
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