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  • Title: Ketorolac for pain management after abdominal surgical procedures in infants.
    Author: Burd RS, Tobias JD.
    Journal: South Med J; 2002 Mar; 95(3):331-3. PubMed ID: 11902701.
    Abstract:
    BACKGROUND: While the use of intravenous ketorolac in infants less than 6 months old has not been previously reported, ketorolac may reduce opioid use and prevent opioid-associated side effects that are frequent in this age group. We reviewed our experience with ketorolac in infants to develop recommendations for using it after abdominal surgery. METHODS: We reviewed the records of 10 infants less than 6 months old who received ketorolac supplemented with morphine and 8 infants who received morphine alone for pain after abdominal surgery. RESULTS: Infants receiving ketorolac required less morphine than infants receiving morphine alone in the first 48 hours after surgery. Four patients receiving ketorolac did not require any supplemental morphine. CONCLUSIONS: Ketorolac reduces the amount of morphine required after abdominal surgery in infants less than 6 months old. The use of ketorolac deserves further study as a method of reducing opioid-associated adverse effects in this patient group.
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