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  • Title: [Bowen disease treated with scanned pulsed high energy CO2 laser. Follow-up of 6 cases].
    Author: Vaïsse V, Clerici T, Fusade T.
    Journal: Ann Dermatol Venereol; 2001 Nov; 128(11):1220-4. PubMed ID: 11908166.
    Abstract:
    INTRODUCTION: Cutaneous Bowen's disease is an intra-epidermal squamous cell carcinoma. PATIENTS AND METHOD: Ten cases of cutaneous Bowen's disease diagnosed among 8 patients were treated by scanned high energy carbon dioxide laser between November 1996, and March 1998. A biopsy was performed in all patients before treatment. RESULTS: The post-treatment follow-up extended from 1 to 4 years with an average follow-up of 2 years and 11 months. Only one patient, whose lesion was located on the auricle, presented a recurrence after one year. The remaining patients did not present any recurrence during their last control: six patients were followed for two years or more and one patient for one year. We demonstrate a histological and clinical correlation between the number of carbon dioxide laser passes before a clinical endpoint and the thickness of the epidermal carcinoma treated. DISCUSSION: This new treatment has comparable efficacy to other treatments. It can be applied to extensive lesions without sequelae except for the risk of residual hypopigmentation.
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