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  • Title: Nobiloside, a new neuraminidase inhibitory triterpenoidal saponin from the marine sponge Erylus nobilis.
    Author: Takada K, Nakao Y, Matsunaga S, van Soest RW, Fusetani N.
    Journal: J Nat Prod; 2002 Mar; 65(3):411-3. PubMed ID: 11908993.
    Abstract:
    A neuraminidase inhibitor, nobiloside (1), was isolated from the marine sponge Erylus nobilis Thiele, 1903. Its structure was determined as a penasterol trisaccharide. The absolute configurations were determined by NMR and chiral GC analysis. It inhibited neuraminidase from the bacterium Clostridium perfringens with an IC50 value of 0.46 microg/mL.
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