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  • Title: Detection of biogenic CO production above vascular cell cultures using a near-room-temperature QC-DFB laser.
    Author: Kosterev AA, Tittel FK, Durante W, Allen M, Kohler R, Gmachl C, Capasso F, Sivco DL, Cho AY.
    Journal: Appl Phys B; 2002 Jan; 74(1):95-9. PubMed ID: 11911164.
    Abstract:
    We report the first application of pulsed, near-room-temperature quantum cascade laser technology to the continuous detection of biogenic CO production rates above viable cultures of vascular smooth muscle cells. A computer-controlled sequence of measurements over a 9-h period was obtained, resulting in a minimum detectable CO production of 20 ppb in a 1-m optical path above a standard cell-culture flask. Data-processing procedures for real-time monitoring of both biogenic and ambient atmospheric CO concentrations are described.
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