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  • Title: Primary Sjögren's syndrome initially manifested by optic neuritis: MRI findings.
    Author: Kadota Y, Tokumaru AM, Kamakura K, Kohyama S, Okizuka H, Kaji T, Kusano S.
    Journal: Neuroradiology; 2002 Apr; 44(4):338-41. PubMed ID: 11914812.
    Abstract:
    We herein describe the MRI findings in a patient clinically diagnosed with primary Sjögren's syndrome (SjS) initially manifested by retrobulbar optic neuritis. A 63-year-old woman suddenly had left ocular pain and progressive visual disturbance. MR T2-weighted images revealed hyperintensity in the left optic nerve, with swelling. Contrast-enhanced T1-weighted images showed no abnormal enhancement. Follow-up MRI 6 months after admission revealed no significant changes in the affected optic nerve. To our knowledge, optic neuritis as a complication of SjS has been reported in ten patients [1, 2, 3, 4, 5, 6] and MRI findings in only one of them [6]. We thought MR images were useful for visualizing optic nerve involvement in SjS and observing its course.
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