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  • Title: Right unilateral and bifrontal electroconvulsive therapy in the treatment of depression: a preliminary study.
    Author: Heikman P, Kalska H, Katila H, Sarna S, Tuunainen A, Kuoppasalmi K.
    Journal: J ECT; 2002 Mar; 18(1):26-30. PubMed ID: 11925518.
    Abstract:
    The short-term outcome of electroconvulsive therapy (ECT) was studied in 24 patients with a current major depressive episode (DSM-IV). Patients were randomized to high dose (400% above the seizure threshold) right unilateral (RUL) ECT, to moderate dose (150% above seizure threshold) RUL ECT, and to low dose (just above seizure threshold) bifrontal (BF) ECT. Primary outcome measures included number of treatments, Hamilton Depression Rating Scale score, and Mini-Mental State Examination score. High dose RUL ECT was associated with a significantly faster response to treatment than low dose BF ECT. Moreover, there was a tendency to a higher response rate with high dose RUL ECT compared with either moderate dose RUL ECT or BF ECT.
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