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  • Title: The characteristics of side-effects of bromperidol in schizophrenic patients.
    Author: Yasui-Furukori N, Kondo T, Ishida M, Tanaka O, Mihara K, Kaneko S, Otani K.
    Journal: Psychiatry Clin Neurosci; 2002 Feb; 56(1):103-6. PubMed ID: 11929578.
    Abstract:
    The characteristics of the side-effects of bromperidol was investigated in 33 acutely exacerbated schizophrenic patients. The most frequently observed side-effects were extrapyramidal symptoms. Acute dystonia developed in 10 of 33 patients, and the mean age was significantly lower (P < 0.05) in patients with dystonia (27.3 +/- 6.2 years) than that in patients without dystonia (41.5 +/- 12.9 years). Plasma drug concentrations were not associated with side-effects. These findings suggest that acute dystonia is affected by age factor, and that daily dosage or monitoring of drug concentration is unlikely to be a useful marker for the prediction of side-effects during bromperidol treatment.
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