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  • Title: [Low flow technique to perform static pressure-volume curve during mechanical ventilation].
    Author: Guo F, Qiu H, Tan Y.
    Journal: Zhonghua Jie He He Hu Xi Za Zhi; 2001 Dec; 24(12):728-31. PubMed ID: 11930701.
    Abstract:
    OBJECTIVE: To describe a fast, simple method to acquire static pressure-volume (P-V) curve of the respiratory system and to compare it with airway occlusion technique. METHODS: ARDS sheep model was induced by intravenously infusing 3-6 micrograms/kg LPS, static P-V curves were determined by low flow technique and airway occlusion technique. Static compliance (Cst), lower inflection point (Pinfd and Pinfb) and airway pressure were compared between the two methods. RESULTS: Pinf were (8.91 +/- 0.82) cm H2O and (8.59 +/- 0.78) cm H2O determined by low flow technique and airway occlusion technique respectively, the correlation between which was good (r = 0.93, P < 0.05). Cst determined by low flow technique was similar to that determined by airway occlusion technique [(19 +/- 7) L/cm H2O vs (20 +/- 7) L/cm H2O, P > 0.05]. The time needed to acquire a static P-V curve by low flow technique was 3-4 minutes versus 30-35 minutes by airway occlusion technique. CONCLUSION: Accuracy and reliability of low flow technique are sufficient for clinical use, it is much less time consuming than the airway occlusion technique.
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