These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Ingestion and digestion of erythocytes by non-irradiated and irradiated macrophages.
    Author: Vorbrodt A, Grabska A, Krzyzowska-Gruca S, Gruca S.
    Journal: Folia Histochem Cytochem (Krakow); 1975; 13(1-2):3-10. PubMed ID: 1193472.
    Abstract:
    The effect of X-rays (1300 R) and gamma irradiation (3000 R) on phagocytic activity of mouse peritoneal macrophages cultivated in vitro was studied using human glutaraldehyde-fixed red blood cells. The peroxidative activity of haemoglobin was cytochemically detected by the DAB method. The obtained results indicate that the applied dose of X-irradiation does not affect the phagocytic activity of macrophages. On the contrary, the gamma irradiation (3000 R) causes acceleration of phagocytic activity of macrophages with concomitant impairment of intracellular digestion of ingested material. Weakened cytochemical reaction for acid phosphatase suggests that sufficiently high doses of irradiation cause some disturbances in the biosynthesis of lysosomal enzymes in exposed macrophages.
    [Abstract] [Full Text] [Related] [New Search]