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  • Title: [Expression of bcl-2, bax and p53 protein in the basal cell carcinoma].
    Author: Yan L, Chen M, Yu G.
    Journal: Hunan Yi Ke Da Xue Xue Bao; 1999; 24(2):179-80. PubMed ID: 11938785.
    Abstract:
    The expression of bcl-2, bax and p53 protein was studied in the basal cell carcinoma with 32 patients by immunohistochemical method. The results showed that bcl-2 protein was positive in 26 patients (81.2%), bax protein was positive in 9 patients(28.1%), and p53 protein was positive in 13 patients (40.6%); there is a negative correlation between the expression of bcl-2 and bax protein(P < 0.05). These findings suggest that apoptosis is suppressed which might cause the production of basal cell carcinoma.
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