These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [DNA content, expression of proliferating cell nuclear antigen and surgical margins in locally advanced laryngeal cancer].
    Author: Wang B, Xia L, Shi Q.
    Journal: Zhonghua Er Bi Yan Hou Ke Za Zhi; 1998 Dec; 33(6):361-3. PubMed ID: 11938851.
    Abstract:
    OBJECTIVE: To probe into the relationship between DNA content, PCNA and prognosis. METHODS: Surgical margins in 34 patients with locally advanced laryngeal cancers were observed by means of antibody to PCNA and DNA content measurements. RESULTS: The results demonstrated that at neoplasm margins of 1.0, 0.5, and 0 cm, PCNA indices were 8.62%, 17.76% and 50.32% and DNA indices were 0.98, 1.082 and 1.436 respectively. There is a significant difference between 1.0, 0.5 and 0 cm. CONCLUSION: Moderate and severe atypical hyperplasia of epithelium (AHE) was different from mild AHE and simple hyperplasia of epithelium in the biologic behavior of fission, proliferation and so on and surgical margins should be kept outside the area of moderate AHE.
    [Abstract] [Full Text] [Related] [New Search]