These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Effect of cadmium on the beta-adrenoreceptor of splenic cell of rats and its immunotoxicity].
    Author: Dong S, Li D, Yu G.
    Journal: Wei Sheng Yan Jiu; 1999 Jul; 28(4):203-5. PubMed ID: 11938975.
    Abstract:
    Rats were given cadmium(Cd) alone or Cd with beta-antagonist in order to study the effect of Cd on beta-adrenoreceptor density of rat splenic cells. The subsets of T-lymphocytes (CD4+, CD8+, CD4+/CD8+) and the proliferation of T lymphocytes were also detected. Cadmium alone stimulated and increased beta-adrenoreceptor density of rat splenic cell membrane. The immunotoxicity of Cd showed that the proliferation of T-lymphocytes was inhibited and the subsets of T cells were changed. But in the animals with beta-antagonist, the immunotoxicity of Cd on T cells was decreased. It is concluded that beta-adrenoreceptor may play an important role in the mechanism of cadmium on cell immunotoxicity.
    [Abstract] [Full Text] [Related] [New Search]